cell aging การใช้

• Telomeres are now known to be the clock of cell aging,
• Guarente and his colleagues hypothesized several years ago to explain why cells age.
• It also marks a watershed advance in the long intractable subject of why human cells age.
• The study of why cells age has been something of a research backwater for many years.
• The key issue tackled by the ACT research has to do with the way living cells age.
• He hoped to find a single mechanism that made cells age, despite the theorists'prediction of many ailments.
• However, the subject's cells age uncontrollably, so Holliston uses the highly addictive drug methotrexate to counter the effect.
• Shay said the telomere, in effect, acts as a biological clock that stops cell division and causes cell aging.
• At Michigan, Villeponteau mostly worked on human gene regulation Villeponteau also studied human cell aging using senescent human cells.
• Scientifically, Sudarshan Kriya improves antioxidant status at the enzyme and the gene level and reduce DNA damage and cell aging.
• Stambrook noted, however, that the chromosome deletion mutation seems to increase in frequency as a colony of stem cells ages.
• Ceramide mediates many cell-stress responses, including the regulation of programmed cell death ( apoptosis ) and cell aging ( senescence ).
• Geron _ named after the Greek word for old man _ set out to prove a theory about why cells age.
• With fundamental discoveries like this, we can understand and begin to manipulate mechanisms which control cell aging and contribute to age-related diseases,
• Basal and wing cells migrate to the anterior of the cornea, while squamous cells age and slough off into the tear film.
• Likewise, the test assumes a normal red blood cell aging process and mix of hemoglobin subtypes ( predominantly HbA in normal adults ).
• Mutant varieties of G6PD can be more unstable than the naturally occurring enzyme, so that their activity declines more rapidly as red cells age.
• But their work is designed to attack the diseases related to cell aging, such as wrinkles, skin ulcers, arteriosclerosis and macular degeneration, which causes blindness.
• As skin cells age, for example, their genes churn out more and more collagenase, an enzyme that breaks down proteins needed to keep wrinkles at bay.
• The idea is to grow the stem cells into adult cells, which can then be kept ageless and dividing through telomerase, an enzyme that controls cell aging.